Title: Car Rental Downtown South San Francisco, CA - Expedia.ca [Downtown South San Francisco Travel Guide](https://expedia.ca/San-Francisco-Downtown-South-San-Francisco.dx553248635976481411)[Hotels in Downtown South San Francisco](https://expedia.ca/Downtown-South-San-Francisco-San-Francisco-Hotels.0-n553248635976481411-0.Travel-Guide-Filter-Hotels)[Flights to San Francisco](https://expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)[Things to do in San Francisco](https://expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)[Downtown South San Francisco Vacations](https://expedia.ca/Downtown-South-San-Francisco.d553248635976481411.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/553248635976481411/298b03a1-de63-4691-b0ab-9761c274ecec.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Downtown South San Francisco Car Rental ## Search and Compare from Car Companies in Downtown South San Francisco ## Featured car rental suppliers Compare from agencies ![car supplier logos](https://forever.travel-assets.com/flex/flexmanager/images/2022/05/16/BEXCA-car-suppliers-logo-desktop.jpg) - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself Members save 10% or more on over 1 million car rentals - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers to unlock big savings ## Top Car Deals in Downtown South San Francisco \* Price found within the past 6 days. Click for updated prices. ### Economy Chevrolet Spark or similar - 4 people San Francisco, California, USA ![Chevrolet Spark](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_EC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Downtown%20South%20San%20Francisco,%20South%20San%20Francisco,%20California,%20United%20States%20of%20America&dpln=553248635976481411&date1=03/03/2026&date2=05/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22economy%22]) ### Compact Ford Focus or similar - 4 people San Francisco, California, USA ![Ford Focus](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_CC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Downtown%20South%20San%20Francisco,%20South%20San%20Francisco,%20California,%20United%20States%20of%20America&dpln=553248635976481411&date1=03/03/2026&date2=05/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22compact%22]) ### Midsize Toyota Corolla or similar - 5 people San Francisco, California, USA ![Toyota Corolla](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_IC.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Downtown%20South%20San%20Francisco,%20South%20San%20Francisco,%20California,%20United%20States%20of%20America&dpln=553248635976481411&date1=03/03/2026&date2=05/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ### SUV Jeep Compass or similar - 5 people San Francisco, California, USA ![Jeep Compass](//images.trvl-media.com/media/content/shared/images/car/Common_90X50/US_SF.png) [](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Downtown%20South%20San%20Francisco,%20South%20San%20Francisco,%20California,%20United%20States%20of%20America&dpln=553248635976481411&date1=03/03/2026&date2=05/03/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22suv%22]) ### Don't see what you're looking for? See all car rentals in Downtown South San Francisco [View all cars](https://expedia.ca/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Downtown%20South%20San%20Francisco,%20South%20San%20Francisco,%20California,%20United%20States%20of%20America&dpln=553248635976481411&date1=03/03/2026&date2=05/03/2026&crfrr=defaultFlex&SearchType=Place) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=CTG_SPRING_PROMO_553248635976481411) ## Frequently asked questions ### How much is a rental car per day in Downtown South San Francisco? ### What happens if I need to cancel my Downtown South San Francisco car reservation? ### Where can I go on a road trip from Downtown South San Francisco? > - You'll find California's Great America and loads of other amazing attractions in Santa Clara. From Downtown South San Francisco, it's roughly 48 kilometres away. > - Located 80 kilometres away, Santa Cruz is also popular with wanderers. Set aside time to check out Santa Cruz Beach Boardwalk while you're here. It's one of the reasons people love coming to this buzzing city. > - Get out into nature and appreciate the serenity at Glacier Point. It's approximately 257 kilometres from Downtown South San Francisco. ### How do I find the best car rental deals in Downtown South San Francisco with Expedia? ### How old do you have to be to rent a car in Downtown South San Francisco? ### What do you need to rent a car in Downtown South San Francisco? ### What is the cheapest car rental in Downtown South San Francisco? ### Can I rent a car for a month or longer in Downtown South San Francisco? ### Where can I find a Downtown South San Francisco car rental if I am younger than 25? ## Car Rental Information | Popular car types: | [SUV](https://www.expedia.ca/lp/b/car-rental/suv?rfrr=car.table.SUV), [Full Size](https://www.expedia.ca/lp/b/car-rental/fullsize?rfrr=car.table.FullSize), [Economy](https://www.expedia.ca/lp/b/car-rental/economy?rfrr=car.table.Economy) | | -------------------------------- | -------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Car suppliers available: | | | Our best deal of the day: | | | Our second best deal of the day: | | | Our third best deal of the day: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.ca/ground-transfers?rfrr=car.table.AirportTransportation) |